From Phoenix & Scottsdale. Flagstaff is located about 150 miles from the Greater Phoenix and Scottsdale area. Use Interstate 17 (Black Canyon Fwy) North directly into Flagstaff AZ. I 17 will merge onto Milton Road which is the main street in Flagstaff.
From Las Vegas. Flagstaff, Arizona is located about 250 miles East of Las Vegas, Nevada. Take Highway 93 South and cross Hoover Dam on the way Kingman, Arizona. From Kingman, take Interstate 40 directly to Flagstaff through Williams AZ.